The Peak of Excellence in Health and Nutrition.
Order Online or Toll Free: 888.674.8558
Free Coupons! Enter the code - save the money! It's that easy!
Shop By Category
Shop By Brand
Home > All Brands > Shop By Interest > Thyroid boosters > Thermal Rage by Primaforce

Thermal Rage by Primaforce

Primaforce
Thyroid boosters
Thermal Rage by Primaforce
No Longer available. Please consider another thermogenic. THERMAL-RAGE™ features a scientifically advanced and highly effective formula that contains proven amounts of Bergenin, a super-high potency green tea extract (Lean Green™--50% EGCG), Tyramine, Evodiamine, Magnolia, and the exciting new compound Bacopa Monnieri which has been shown to support thyroid health. Thermal Rage™ will not only help strip away fat and preserve lean muscle, it also provides energy and mental focus to help propel you in the gym and during everyday life. Thermal Rage can help:
  • Burn more fat
  • Maximize energy and mental focus
  • Promote increased metabolism
  • Support thyroid health even on reduced calories
  • Curb hunger
  • Prevent insulin resistance
  • Halt Catabolism Here is the rundown on Thermal Rage’s Ultimate Thermogenic Energizing™ Components:
    Bergenin
    Much like the EGCG found in Green Tea, Bergenin has been shown to be increase the lipolytic action of other compounds acting on the adrenergic system. Studies have confirmed that it markedly increases lipolysis caused by adrenergic hormones such as norepinephrine, and even opposes the lipogenic (fat building) actions of the hormone insulin. Some of the known actions in which Bergenin fights fat involve increased norepinephrine binding to fat cells and the inhibition or blocking of the PPAR-gamma receptor which is responsible for the accumulation of fat and maturation of fat cells. Tyramine
    A compound that is found in small quantities in many foods such as aged cheeses, beer, wine and processed meats, is also produced in the body by the amino acid tyrosine. Taking supplemental tyramine causes more norepinephrine (NE) – a neurotransmitter that increases metabolism and the use of fat as fuel – to be released from nerve cells. NE has also been a target for some of the newer antidepressant drugs. Because of the structural similarity, tyramine can displace NE, leading the body to release more of it. Human studies have confirmed that tyramine is capable of increasing NE levels in the bloodstream. As an added bonus, it is possible that tyramine also increases the levels of dopamine (another neurotransmitter with appetite suppressing and antidepressant effects), although the research is controversial on this point. Tyramine has also been found to increase insulin sensitivity. Using an animal model of diabetes, researchers found that tyramine increased glucose disposal and prevented hyperglycemia. With the combination of increased neurotransmitter levels and improved insulin sensitivity, tyramine could confer multiple benefits, including appetite suppression, fat loss, and a muscle sparing effect. New evidence suggests that tyramine may halp enhance leptin sensitivity, which can be tremendously important when attempting to lose bodyfat and curb hunger. Bacopa monnieri
    Stress is one of the primary problems on a diet, and can be a serious impediment to successful weight loss. Because of this, a class of drugs known as adaptogens is becoming increasingly popular among bodybuilders. Adaptogens are essentially drugs or herbs that increase the body’s resistance against various physical and psychological stressors. An Ayuervedic herb also as brahmi, Bacopa Monnieri has been used for centuries in India to enhance memory and reduce stress. Bacopa is one of the better known adaptogens, and it can effectively blunt stress-induced changes in the levels of various hormones and enzymes. It has been described in the medical literature as having “potent adaptogenic activity.” Additionally, bacopa has cognition enhancing properties, even in healthy humans, but only after it has been regularly administered for some time. In one placebo-controlled study, after twelve weeks of bacopa administration, people given the herb had improved scores on tests of verbal learning, memory consolidation, and early information processing. Animal studies also indicate bacopa to have antiinflammatory, anticancer, antiepileptic, anxiolytic (anxiety reducing), and antidepressant properties. As an added bonus, it’s possible that bacopa could increase thyroid hormone levels, leading to an increase in metabolic rate. In one study, bacopa administration showed it can increase hormone levels by more than 40%. Thyroid hormones play a major role in regulating the metabolic rate of the cells, increasing the pace at which your body burns calories. All in all, bacopa is an effective supplement and one of the best options for combating stress due to diet and heavy training. Magnolia
    For thousands of years, magnolia bark has been used in Traditional Chinese Medicine to boost energy and reduce stress. Preliminary research shows magnolia not only helps to lower cortisol (elevated cortisol leads to fat storage, particularly around the waistline), but actually helps fat leave fat cells. Once the fat departs from the cell, it can travel to active tissues to be used for energy. Green Tea
    Green tea extract has been a popular supplement for a while, but more and more research is confirming not only its many health benefits, but its ability to promote fat loss. In addition to multiple animal studies showing green tea to lead to fat loss published just this year, a three month double-blind, placebo controlled study on thirty men was published in the January 2005 issue of the American Journal of Clinical Nutrition. Compared to the placebo group, those who ingested catechins (the beneficial compounds in green tea that extracts are standardized for) daily lost more weight and more fat. While the earlier research was more preliminary, this study confirms the ability of green tea to lead to fat loss in humans. Recent research has also given us a better picture of how green tea leads to fat loss. The more well-known mechanisms are catechol-O-methyl-transferase (COMT) inhibition, decreased dietary fat absorption, and increased levels of some hormones that suppress the appetite. A study published last year suggested yet another mechanism: when given to rats, green tea decreased the activity of glucose transporter 4 (GLUT4) in fat tissue, while increasing GLUT4 activity in muscle tissue. What this means is that fuel was being shunted away from fat and towards muscle. Not only does green tea facilitate weight loss, it can also lead to the preferential loss of fat over muscle. This is a great asset, since maintaining muscle mass is one of the hardest things to do on a diet. A new study has discovered the phytochemicals in green tea are better use by the body in supplemental form rather than from actual green tea. The active ingredients in Lean Green™, the super-potent green tea extract found in Thermal Rage, are catechins, and the main catechin responsible for the thermogenic effect of green tea extract is epigallocatechin gallate (EGCG). Studies show it can increase metabolism by about 4%. That equates to more than 100 extra calories burned per day for most males. EGCG inhibits the enzyme responsible for the degradation of NE. By preventing NE breakdown, its fat burning effect is stronger and lasts longer. Caffeine
    caffeine. in a central nervous system stimulant (CNS) and is known as the king of all stimulants. Caffeine has well known thermogenic properties in humans; increasing the rate of lipolysis and total energy expenditure, and decreasing food intake. It has also been shown to help increase fat-burning during exercise and improve performance. Caffeine is particularly effective for fat loss when used in conjunction with an agent that causes release of NE or other catecholamines, such as tyramine. Caffeine also may exhibit a synergistic relationship for fat loss with EGCG, a component of green tea. This is because EGCG inhibits COMT, an enzyme that breaks down NE and other catecholamines. Niacin
    Niacin is an essential B vitamin. Niacin contributes to healthy cardiovascular function, nervous system function, and immune function. Niacin also helps support healthy cholesterol levels and can help remove fats (triglycerides) from tissues and the bloodstream. Evodiamine
    Evodiamine is a compound that comes from Edovia fruits, which are used as a medicine in China. It is related to capsaicin, which is responsible for the sensation of heat caused by hot peppers. These substances act on receptors in the body known as vanilloid receptors, which can lead to a variety of effects. One of the changes noted after evodiamine administration in one study was a reduction in body fat, along with reduced cholesterol and triglyceride levels. These changes occurred at relatively low doses of the drug. This study also demonstrated that (contrary to popular belief) evodiamine should not necessarily be expected to alter body temperature, as it has effects that both increase and decrease body temperature which cancel out. However, according to another study, it may at least prevent body temperature from dropping below normal. Not only does evodiamine lead to fat loss by helping thermogenesis, it also suppresses the appetite. It does this by increasing the levels of cholecystokinin (CCK), a hormone that acts as a natural appetite suppressant. As with the other supplements we have discussed, a number of possible health benefits have been identified. Evodiamine has been found to stop or slow the spread of prostate cancer, leukemia, melanoma, cervical cancer, fibrosarcoma, and multiple drug resistant breast cancer cells. Animal studies have also found that it has beneficial effects on the cardiovascular system, can reduce hypoxia, and is a potential treatment for erectile dysfunction because of its vasodilating effect. With the low dosage required, multiple mechanisms of action, and possible health benefits, evodiamine is another potential candidate for the next safe and effective fat loss aid. Based on it’s scientifically-advanced formula, Thermal Rage is clearly the most complete Thermogenic Energizer available. If you’re ready to feel what the fat loss and energy “RAGE” is all about, try Thermal Rage today. You’ll gain the energy and lose the fat! Serving Size: 2 Capsules
    Servings Per Container: 60
    Amount Per Serving
    Caffeine (as Caffeine USP and Green Tea Extract) 250 MG†
    Grean Tea (Lean Green™ 50% EGCG) 200 MG†
    Bacopa Monnieri 200 MG†
    Tyramine 60 MG†
    Niacin 50 MG†
    Bergenin 50 MG†
    Evodiamine 40 MG†
    Magnolia Extract (standardized to 30% magnolol) 25 MG†
    † Daily Value Not Established. As a dietary supplement, take one or two capsules in the morning prior to breakfast and one or two capsules six hours later with 8 ounces of water. To assess tolerance, begin with ½ the recommended dose (one capsule). Do not exceed four capsules in any 24-hour period. Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness and occasional rapid heartbeat. Do not use if you are diabetic. Keep out of reach of children. Always consult a physician prior to using any dietary supplements. Altern Med Rev. 2004 Mar;9(1):79-85. Bacopa monniera. Monograph. [No authors listed] Am J Clin Nutr. 2005 Jan;81(1):122-9. Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. Nagao T, Komine Y, Soga S, Meguro S, Hase T, Tanaka Y, Tokimitsu I. Biofactors. 2004;22(1-4):135-40. Anti-obesity actions of green tea: possible involvements in modulation of the glucose uptake system and suppression of the adipogenesis-related transcription factors. Ashida H, Furuyashiki T, Nagayasu H, Bessho H, Sakakibara H, Hashimoto T, Kanazawa K. Am J Clin Nutr., 80(6):1,558-1,564, 2004 Henning, SA., et al. Bioavailability and and antioxidant activity of tea flavanoids after consumption of green tea, black tea, or a green tea extract supplement. J Biol Chem. 2005 Feb 14; [Epub ahead of print]. Evodiamine abolishes constitutive and inducible NF-kappa B activation by inhibiting Ikappa Balpha kinase activation, thereby suppressing NF-kappa B-regulated antiapoptotic and metastatic gene expression, upregulating apoptosis, and inhibiting invasion. Takada Y, Kobayashi Y, Aggarwal BB. Carcinogenesis. 2005 Feb 10; [Epub ahead of print]. Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae Fructus, in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo. Liao CH, Pan SL, Guh JH, Chang YL, Pai HC, Lin CH, Teng CM. Chem Pharm Bull (Tokyo). 1991 Mar;39(3):690-2. Pharmacological properties of galenical preparation. XIV. Body temperature retaining effect of the Chinese traditional medicine, "goshuyu-to" and component crude drugs. Kano Y, Zong QN, Komatsu K. Circulation. 2003 May 20;107(19):2475-9. Epub 2003 Apr 21. Neurovascular dissociation with paradoxical forearm vasodilation during systemic tyramine administration. Jacob G, Costa F, Vincent S, Robertson D, Biaggioni I. Circulation. 2004 Jan 27;109(3):E17-8. Vasodilation during systemic tyramine administration response. Goldstein DS, Holmes C, Jacob G, Costa F, Vincent S, Robertson D, Biaggioni I. J Ethnopharmacol. 1989 Nov;27(1-2):185-92. Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit. Yamahara J, Yamada T, Kitani T, Naitoh Y, Fujimura H. J Ethnopharmacol. 2002 Jul;81(2):281-5. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. Kar A, Panda S, Bharti S. Eur J Pharmacol. 2002 Dec 20;457(2-3):169-76. Effects of evodiamine on gastrointestinal motility in male rats. Wu CL, Hung CR, Chang FY, Lin LC, Pau KY, Wang PS. Eur J Pharmacol. 2002 Jun 20;446(1-3):151-9. Pharmacological profile of evodiamine in isolated rabbit corpus cavernosum. Chiou WF, Chen CF. Pharmacol Biochem Behav. 2003 Jul;75(4):823-30. Adaptogenic effect of Bacopa monniera (Brahmi). Rai D, Bhatia G, Palit G, Pal R, Singh S, Singh HK. Planta Med. 2001 Oct;67(7):628-33. Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist. Kobayashi Y, Nakano Y, Kizaki M, Hoshikuma K, Yokoo Y, Kamiya T. Phytomedicine. 2002 Apr;9(3):207-11. Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats. Sairam K, Dorababu M, Goel RK, Bhattacharya SK. J. Pharmacy and Pharmacology, 2000 52(11):1,425-1,429. The anxiolytic effect of two oriental herbal drugs in Japan atrtributed to honokiol from magnolia bark. Kuribara, H., Kishi, E., Hattori, N., et al. J Physiol Biochem. 2003 Sep;59(3):225-32. Effect of prolonged treatment with tyramine on glucose tolerance in streptozotocin-induced diabetic rats. Visentin V, Marq P, Bour S, Subra C, Prevot D, Morin N, Valet P, Monje MC, Nepveu F, Carpene C. Am J Clin Nutr. 2003 Jun;77(6):1442-7. Effect of chewing gum containing nicotine and caffeine on energy expenditure and substrate utilization in men. Jessen AB, Toubro S, Astrup A. Clin Exp Pharmacol Physiol. 2002 May-Jun;29(5-6):391-4. Effects of caffeine on the uncoupling protein family in obese yellow KK mice. Kogure A, Sakane N, Takakura Y, Umekawa T, Yoshioka K, Nishino H, Yamamoto T, Kawada T, Yoshikawa T, Yoshida T. Br J Nutr. 2001 Feb;85(2):203-11. Combined effects of red pepper and caffeine consumption on 24 h energy balance in subjects given free access to foods. Yoshioka M, Doucet E, Drapeau V, Dionne I, Tremblay A. Brain Cogn. 2003 Feb;51(1):143-54. Effects of mental workload and caffeine on catecholamines and blood pressure compared to performance variations. Papadelis C, Kourtidou-Papadeli C, Vlachogiannis E, Skepastianos P, Bamidis P, Maglaveras N, Pappas K. JAMA 2003 Mar 26;289(12):1537-45. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta-analysis. Shekelle PG, Hardy ML, Morton SC, Maglione M, Mojica WA, Suttorp MJ, Rhodes SL, Jungvig L, Gagne J. Phytomedicine. 2002 Jan;9(1):3-8. Recent findings of green tea extract AR25 (Exolise) and its activity for the treatment of obesity. Chantre P, Lairon D.
    http://www.paramount-supplements.comthra120cabyp.html
    $20.95
  • Thermal Rage by Primaforce
    Regular Price:$29.95
    Paramount Price:$20.95You save 30%
    Package Insurance? :
    Rating:
    Recommended items
    Phenadrine by APS 60ctPhenadrine by APS 60ct $33.49
    Package Insurance? :
    VenEVOL by Evo Labs 90ctVenEVOL by Evo Labs 90ct $42.99
    Package Insurance? :
    View Less
    This item is currently out of stock!


    Description
    Quantity Pricing
    Reviews
    No Longer available. Please consider another thermogenic.



    THERMAL-RAGE™ features a scientifically advanced and highly effective formula that contains proven amounts of Bergenin, a super-high potency green tea extract (Lean Green™--50% EGCG), Tyramine, Evodiamine, Magnolia, and the exciting new compound Bacopa Monnieri which has been shown to support thyroid health. Thermal Rage™ will not only help strip away fat and preserve lean muscle, it also provides energy and mental focus to help propel you in the gym and during everyday life. Thermal Rage can help:

  • Burn more fat
  • Maximize energy and mental focus
  • Promote increased metabolism
  • Support thyroid health even on reduced calories
  • Curb hunger
  • Prevent insulin resistance
  • Halt Catabolism

    Here is the rundown on Thermal Rage’s Ultimate Thermogenic Energizing™ Components:


    Bergenin
    Much like the EGCG found in Green Tea, Bergenin has been shown to be increase the lipolytic action of other compounds acting on the adrenergic system. Studies have confirmed that it markedly increases lipolysis caused by adrenergic hormones such as norepinephrine, and even opposes the lipogenic (fat building) actions of the hormone insulin. Some of the known actions in which Bergenin fights fat involve increased norepinephrine binding to fat cells and the inhibition or blocking of the PPAR-gamma receptor which is responsible for the accumulation of fat and maturation of fat cells.



    Tyramine
    A compound that is found in small quantities in many foods such as aged cheeses, beer, wine and processed meats, is also produced in the body by the amino acid tyrosine. Taking supplemental tyramine causes more norepinephrine (NE) – a neurotransmitter that increases metabolism and the use of fat as fuel – to be released from nerve cells. NE has also been a target for some of the newer antidepressant drugs.

    Because of the structural similarity, tyramine can displace NE, leading the body to release more of it. Human studies have confirmed that tyramine is capable of increasing NE levels in the bloodstream. As an added bonus, it is possible that tyramine also increases the levels of dopamine (another neurotransmitter with appetite suppressing and antidepressant effects), although the research is controversial on this point. Tyramine has also been found to increase insulin sensitivity. Using an animal model of diabetes, researchers found that tyramine increased glucose disposal and prevented hyperglycemia. With the combination of increased neurotransmitter levels and improved insulin sensitivity, tyramine could confer multiple benefits, including appetite suppression, fat loss, and a muscle sparing effect. New evidence suggests that tyramine may halp enhance leptin sensitivity, which can be tremendously important when attempting to lose bodyfat and curb hunger.



    Bacopa monnieri
    Stress is one of the primary problems on a diet, and can be a serious impediment to successful weight loss. Because of this, a class of drugs known as adaptogens is becoming increasingly popular among bodybuilders. Adaptogens are essentially drugs or herbs that increase the body’s resistance against various physical and psychological stressors. An Ayuervedic herb also as brahmi, Bacopa Monnieri has been used for centuries in India to enhance memory and reduce stress. Bacopa is one of the better known adaptogens, and it can effectively blunt stress-induced changes in the levels of various hormones and enzymes. It has been described in the medical literature as having “potent adaptogenic activity.”

    Additionally, bacopa has cognition enhancing properties, even in healthy humans, but only after it has been regularly administered for some time. In one placebo-controlled study, after twelve weeks of bacopa administration, people given the herb had improved scores on tests of verbal learning, memory consolidation, and early information processing. Animal studies also indicate bacopa to have antiinflammatory, anticancer, antiepileptic, anxiolytic (anxiety reducing), and antidepressant properties.

    As an added bonus, it’s possible that bacopa could increase thyroid hormone levels, leading to an increase in metabolic rate. In one study, bacopa administration showed it can increase hormone levels by more than 40%. Thyroid hormones play a major role in regulating the metabolic rate of the cells, increasing the pace at which your body burns calories. All in all, bacopa is an effective supplement and one of the best options for combating stress due to diet and heavy training.



    Magnolia
    For thousands of years, magnolia bark has been used in Traditional Chinese Medicine to boost energy and reduce stress. Preliminary research shows magnolia not only helps to lower cortisol (elevated cortisol leads to fat storage, particularly around the waistline), but actually helps fat leave fat cells. Once the fat departs from the cell, it can travel to active tissues to be used for energy.



    Green Tea
    Green tea extract has been a popular supplement for a while, but more and more research is confirming not only its many health benefits, but its ability to promote fat loss. In addition to multiple animal studies showing green tea to lead to fat loss published just this year, a three month double-blind, placebo controlled study on thirty men was published in the January 2005 issue of the American Journal of Clinical Nutrition. Compared to the placebo group, those who ingested catechins (the beneficial compounds in green tea that extracts are standardized for) daily lost more weight and more fat. While the earlier research was more preliminary, this study confirms the ability of green tea to lead to fat loss in humans.

    Recent research has also given us a better picture of how green tea leads to fat loss. The more well-known mechanisms are catechol-O-methyl-transferase (COMT) inhibition, decreased dietary fat absorption, and increased levels of some hormones that suppress the appetite. A study published last year suggested yet another mechanism: when given to rats, green tea decreased the activity of glucose transporter 4 (GLUT4) in fat tissue, while increasing GLUT4 activity in muscle tissue. What this means is that fuel was being shunted away from fat and towards muscle. Not only does green tea facilitate weight loss, it can also lead to the preferential loss of fat over muscle. This is a great asset, since maintaining muscle mass is one of the hardest things to do on a diet.

    A new study has discovered the phytochemicals in green tea are better use by the body in supplemental form rather than from actual green tea. The active ingredients in Lean Green™, the super-potent green tea extract found in Thermal Rage, are catechins, and the main catechin responsible for the thermogenic effect of green tea extract is epigallocatechin gallate (EGCG). Studies show it can increase metabolism by about 4%. That equates to more than 100 extra calories burned per day for most males. EGCG inhibits the enzyme responsible for the degradation of NE. By preventing NE breakdown, its fat burning effect is stronger and lasts longer.



    Caffeine
    caffeine. in a central nervous system stimulant (CNS) and is known as the king of all stimulants. Caffeine has well known thermogenic properties in humans; increasing the rate of lipolysis and total energy expenditure, and decreasing food intake. It has also been shown to help increase fat-burning during exercise and improve performance. Caffeine is particularly effective for fat loss when used in conjunction with an agent that causes release of NE or other catecholamines, such as tyramine.

    Caffeine also may exhibit a synergistic relationship for fat loss with EGCG, a component of green tea. This is because EGCG inhibits COMT, an enzyme that breaks down NE and other catecholamines.



    Niacin
    Niacin is an essential B vitamin. Niacin contributes to healthy cardiovascular function, nervous system function, and immune function. Niacin also helps support healthy cholesterol levels and can help remove fats (triglycerides) from tissues and the bloodstream.



    Evodiamine
    Evodiamine is a compound that comes from Edovia fruits, which are used as a medicine in China. It is related to capsaicin, which is responsible for the sensation of heat caused by hot peppers. These substances act on receptors in the body known as vanilloid receptors, which can lead to a variety of effects. One of the changes noted after evodiamine administration in one study was a reduction in body fat, along with reduced cholesterol and triglyceride levels. These changes occurred at relatively low doses of the drug. This study also demonstrated that (contrary to popular belief) evodiamine should not necessarily be expected to alter body temperature, as it has effects that both increase and decrease body temperature which cancel out. However, according to another study, it may at least prevent body temperature from dropping below normal.

    Not only does evodiamine lead to fat loss by helping thermogenesis, it also suppresses the appetite. It does this by increasing the levels of cholecystokinin (CCK), a hormone that acts as a natural appetite suppressant. As with the other supplements we have discussed, a number of possible health benefits have been identified. Evodiamine has been found to stop or slow the spread of prostate cancer, leukemia, melanoma, cervical cancer, fibrosarcoma, and multiple drug resistant breast cancer cells. Animal studies have also found that it has beneficial effects on the cardiovascular system, can reduce hypoxia, and is a potential treatment for erectile dysfunction because of its vasodilating effect. With the low dosage required, multiple mechanisms of action, and possible health benefits, evodiamine is another potential candidate for the next safe and effective fat loss aid. Based on it’s scientifically-advanced formula, Thermal Rage is clearly the most complete Thermogenic Energizer available. If you’re ready to feel what the fat loss and energy “RAGE” is all about, try Thermal Rage today. You’ll gain the energy and lose the fat!



    Serving Size: 2 Capsules
    Servings Per Container: 60


    Amount Per Serving
    Caffeine (as Caffeine USP and Green Tea Extract) 250 MG†
    Grean Tea (Lean Green™ 50% EGCG) 200 MG†
    Bacopa Monnieri 200 MG†
    Tyramine 60 MG†
    Niacin 50 MG†
    Bergenin 50 MG†
    Evodiamine 40 MG†
    Magnolia Extract (standardized to 30% magnolol) 25 MG†


    † Daily Value Not Established.



    As a dietary supplement, take one or two capsules in the morning prior to breakfast and one or two capsules six hours later with 8 ounces of water. To assess tolerance, begin with ½ the recommended dose (one capsule). Do not exceed four capsules in any 24-hour period.



    Limit the use of caffeine-containing medications, foods, or beverages while taking this product because too much caffeine may cause nervousness, irritability, sleeplessness and occasional rapid heartbeat. Do not use if you are diabetic. Keep out of reach of children. Always consult a physician prior to using any dietary supplements.



    Altern Med Rev. 2004 Mar;9(1):79-85. Bacopa monniera. Monograph. [No authors listed]

    Am J Clin Nutr. 2005 Jan;81(1):122-9. Ingestion of a tea rich in catechins leads to a reduction in body fat and malondialdehyde-modified LDL in men. Nagao T, Komine Y, Soga S, Meguro S, Hase T, Tanaka Y, Tokimitsu I.

    Biofactors. 2004;22(1-4):135-40. Anti-obesity actions of green tea: possible involvements in modulation of the glucose uptake system and suppression of the adipogenesis-related transcription factors. Ashida H, Furuyashiki T, Nagayasu H, Bessho H, Sakakibara H, Hashimoto T, Kanazawa K.

    Am J Clin Nutr., 80(6):1,558-1,564, 2004 Henning, SA., et al. Bioavailability and and antioxidant activity of tea flavanoids after consumption of green tea, black tea, or a green tea extract supplement.

    J Biol Chem. 2005 Feb 14; [Epub ahead of print]. Evodiamine abolishes constitutive and inducible NF-kappa B activation by inhibiting Ikappa Balpha kinase activation, thereby suppressing NF-kappa B-regulated antiapoptotic and metastatic gene expression, upregulating apoptosis, and inhibiting invasion. Takada Y, Kobayashi Y, Aggarwal BB.

    Carcinogenesis. 2005 Feb 10; [Epub ahead of print]. Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae Fructus, in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo. Liao CH, Pan SL, Guh JH, Chang YL, Pai HC, Lin CH, Teng CM.

    Chem Pharm Bull (Tokyo). 1991 Mar;39(3):690-2. Pharmacological properties of galenical preparation. XIV. Body temperature retaining effect of the Chinese traditional medicine, "goshuyu-to" and component crude drugs. Kano Y, Zong QN, Komatsu K.

    Circulation. 2003 May 20;107(19):2475-9. Epub 2003 Apr 21. Neurovascular dissociation with paradoxical forearm vasodilation during systemic tyramine administration. Jacob G, Costa F, Vincent S, Robertson D, Biaggioni I.

    Circulation. 2004 Jan 27;109(3):E17-8. Vasodilation during systemic tyramine administration response. Goldstein DS, Holmes C, Jacob G, Costa F, Vincent S, Robertson D, Biaggioni I.

    J Ethnopharmacol. 1989 Nov;27(1-2):185-92. Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit. Yamahara J, Yamada T, Kitani T, Naitoh Y, Fujimura H.

    J Ethnopharmacol. 2002 Jul;81(2):281-5. Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice. Kar A, Panda S, Bharti S.

    Eur J Pharmacol. 2002 Dec 20;457(2-3):169-76. Effects of evodiamine on gastrointestinal motility in male rats. Wu CL, Hung CR, Chang FY, Lin LC, Pau KY, Wang PS.

    Eur J Pharmacol. 2002 Jun 20;446(1-3):151-9. Pharmacological profile of evodiamine in isolated rabbit corpus cavernosum. Chiou WF, Chen CF.

    Pharmacol Biochem Behav. 2003 Jul;75(4):823-30. Adaptogenic effect of Bacopa monniera (Brahmi). Rai D, Bhatia G, Palit G, Pal R, Singh S, Singh HK.

    Planta Med. 2001 Oct;67(7):628-33. Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist. Kobayashi Y, Nakano Y, Kizaki M, Hoshikuma K, Yokoo Y, Kamiya T.

    Phytomedicine. 2002 Apr;9(3):207-11. Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats. Sairam K, Dorababu M, Goel RK, Bhattacharya SK.

    J. Pharmacy and Pharmacology, 2000 52(11):1,425-1,429. The anxiolytic effect of two oriental herbal drugs in Japan atrtributed to honokiol from magnolia bark. Kuribara, H., Kishi, E., Hattori, N., et al.

    J Physiol Biochem. 2003 Sep;59(3):225-32. Effect of prolonged treatment with tyramine on glucose tolerance in streptozotocin-induced diabetic rats. Visentin V, Marq P, Bour S, Subra C, Prevot D, Morin N, Valet P, Monje MC, Nepveu F, Carpene C.

    Am J Clin Nutr. 2003 Jun;77(6):1442-7. Effect of chewing gum containing nicotine and caffeine on energy expenditure and substrate utilization in men. Jessen AB, Toubro S, Astrup A.

    Clin Exp Pharmacol Physiol. 2002 May-Jun;29(5-6):391-4. Effects of caffeine on the uncoupling protein family in obese yellow KK mice. Kogure A, Sakane N, Takakura Y, Umekawa T, Yoshioka K, Nishino H, Yamamoto T, Kawada T, Yoshikawa T, Yoshida T.

    Br J Nutr. 2001 Feb;85(2):203-11. Combined effects of red pepper and caffeine consumption on 24 h energy balance in subjects given free access to foods. Yoshioka M, Doucet E, Drapeau V, Dionne I, Tremblay A.

    Brain Cogn. 2003 Feb;51(1):143-54. Effects of mental workload and caffeine on catecholamines and blood pressure compared to performance variations. Papadelis C, Kourtidou-Papadeli C, Vlachogiannis E, Skepastianos P, Bamidis P, Maglaveras N, Pappas K.

    JAMA 2003 Mar 26;289(12):1537-45. Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta-analysis. Shekelle PG, Hardy ML, Morton SC, Maglione M, Mojica WA, Suttorp MJ, Rhodes SL, Jungvig L, Gagne J.

    Phytomedicine. 2002 Jan;9(1):3-8. Recent findings of green tea extract AR25 (Exolise) and its activity for the treatment of obesity. Chantre P, Lairon D.
  • Quantity Price Available
    1+$29.95 ea.
    Hybrid Performance NutritionCON-CRETDymatizePNI - Premium NutriceuticalsGerman American Technologies (GAT)360 CutMuscleMedsPro SuppsRSP NutritionFusion Bodybuilding Supplements
    Categories
    Customers Say...

    Best value I could find on the internet for the product I wanted! Plus they provided excellent ... read more

    S. Mache - Bryan, TX

    Newsletter Signup
    Join our mailing list for more special offers and savings!
    Help Wounded Warriors
    Paramount-Supplements.com

    SECURE ONLINE ORDERING
    during checkout process.


    TO PLACE AN ORDER BY PHONE CALL 1-888-674-8558

    Email: Paramount-Supplements
  • This shopping cart employs the highest industry strength security: 256 bit SSL E-commerce by Yahoo! We proudly accept Visa, Master Card, American Express, Discover, and PayPal
    © 2013 Paramount-Supplements.
    All Rights Reserved.
    Yahoo! Store by Solid Cactus
    Paramount-Supplements.com is upfront Nextag Seller PriceGrabber User Ratings for paramount-suplements Read Your Store Reviews Discount Supplements
    DISCLAIMER: The information on this website reflects the opinion of our staff and manufacturer's and should not be interpreted as medical advice. The descriptions and statements accompanying these products have not been evaluated by the Food and Drug Administration. These descriptions, statements and products are not intended to diagnose, mitigate, treat, cure or prevent any disease. Theyare for use by healthy adults only. Consult your physician before beginning any program. Keep all products out of the reach of children.The opinions expressed are those of the authors of articles and manufacturers of products referenced on this website and do not necessarily state or reflect the views of Paramount-Supplements. Publication on this website should not be considered an endorsement. Paramount-Supplements and its employees do not express or imply any warranty or assume any legal liability or responsibility for the accuracy, completeness, or usefulness of any information on this website. Paramount-Supplements will not be held liable for any direct orindirect loss or damage arising under this disclaimer or in connection with our website. By using our website, you accept this disclaimer in full.The information on this website is the property of Paramount-Supplements. It is being made available free of charge. Unlessproviding full attribution, website users must not republish material from this website, including republication on another website, except solely for personal use. Website users must not redistribute any materials or information published on this website.